Targeted Protein Degradation

PROTAC® or molecular glues rely on the ubiquitin proteasome system (UPS) to degrade their target protein. Our biology department offers a suite of assays to develop and characterize this new class of therapeutic agents and has already supported more than 16 projects for targeted protein degradation drug development, providing flexible and know-how expertise. Paraza Pharma chemistry team can support PROTAC® and glue design and synthesis, while our DMPK team is ready to profile physicochemical properties/ADME/PK.

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