Chemical Sciences

Propelling your drug discovery program with our streamlined chemistry solutions

Our dynamic chemical science team has a proven track record in medicinal chemistry, chemical development, computational chemistry, and analytical chemistry. Our highly skilled and result-oriented discovery team has contributed to multiple successful programs, maintaining an exceptional degree of client satisfaction. We understand drug discovery and will work with you to design the custom collaboration necessary to advance your project.


“In the last two and half years, with your help, we have set the company on a successful path. You have made critical contributions to creative problem-solving that has helped us achieve these great milestones.”

Experience a collaboration like nowhere else

We offer a multidisciplinary and collaborative environment which enables the exchange of ideas, germination of new concepts, and flawless execution through state-of-the-art chemistry capabilities. Find out how we can advance your project and help you reach your next milestones.

Medicinal Chemistry

  • Multi-parameter optimization from hits through candidates
  • Development of SAR enabling routes
  • Scaffold hopping and IP expansion
  • Management of external resources
  • Synthesis of chemical probes

Chemical Development

  • Custom synthesis and route development
  • Process development and scale-up
  • Parallel synthesis
  • Peptide synthesis
  • Technology transfer to CDMO

Computer-Aided Drug Design (CADD)

  • Structure-based design
  • Ligand-based design
  • Virtual screening
  • MD simulation
  • ADMET prediction
  • AI-driven drug discovery

Analysis & Preparative Services

  • Method development
  • Chiral and achiral separation (milligram to gram scale)

State-of-the art instrumentation

Medicinal Chemistry
  • Access to more than 40,000 chemicals in inventory
  • Chemistry database
  • Automated purification systems
  • 400 and 500 MHz NMR spectrometers
  • Open access UPLC-MS systems
  • Open access Prep-MS HPLC systems
  • Microwave synthesizers
  • Parr shakers
  • Ozone generators
  • Photoreactors (Penn PhD)
  • Electrochemistry kits (IKA)
  • Hydrogenation bombs
  • Walk-in fume hoods
  • Reactors (up to 30 L)
  • Jacketed filter dryer (5 L capacity)
  • Photochemical reactors (up to 2 L)
  • Electrochemical reactors (up to 4 L)
  • Large-scale rotary evaporator (20 L capacity)
  • Flow chemistry setup
  • HT-12 GeneVac evaporation system
  • Peptide synthesizer
  • Karl-Fischer titrator
  • Polarimeter
  • Multi-experiment automated workstation (Tecan)
  • UPLC-UV-MS systems
  • HPLC-UV systems
  • HPLC-UV-MS systems
  • LC-UV-ELSD-MS systems
  • UPC2-UV-MS system
  • UPC2-UV system
  • SFC-UV-MS Prep 15 systems
  • Auto purification semi-prep systems

Give us a call or send us an email

If you want to learn more about the Paraza difference, contact us to discuss your specific needs.