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In Vitro DMPK Associate Scientist or Senior Associate Scientist

Paraza Pharma, Inc.

Paraza Pharma, Inc. is a fast-growing pharmaceutical research company offering a dynamic and collaborative work environment where scientific excellence, innovation and creativity are at the forefront. Here, diversity, new points of view and a creative spirit are valued and considered as real assets. We provide our employees with ongoing support, training and development opportunities to expand their horizons while contributing to our shared passion for Drug Discovery.

Job Description

As a member of the Drug Metabolism and Pharmacokinetic (DMPK) group, the candidate will be in charge of performing standardized protocols, aiming at the screening and profiling of drug candidates on the basis of their in vitro ADME properties.  The candidate will also be involved in the validation and/or establishment of new in vitro assays. The work will mainly consist of classical bench work and cell culture and data analysis.

The successful candidate possesses 2 years of experience in DMPK or in a related field (biology, biochemistry) with a good knowledge of the different biological mechanisms involved in the absorption, distribution, metabolism and excretion of novel chemical entity.  Experience in cell culture will be considered an asset.  Good communication skills and capacity to deliver results in a stringent schedule while maintaining excellent work quality is essential.

Major Responsibilities 

  • Culture and treatment of different cell lines.
  • Participate actively in compound screening campaigns by performing in vitro assessments involving biological matrices.
  • Data analysis and reporting.
  • Participate actively in the establishment/improvement of experimental methodologies.

Qualifications 

  • Master university degree in biochemistry, biology, pharmacology or related scientific field;
  • At least 2 years of experience in the industry;
  • Demonstrated skills working with cells (hepatocytes, Caco-2, MDCK considered an asset);
  • Demonstrated team work spirit with capability to succeed in a fast-paced environment, working on multiple projects with constantly changing priorities and deadlines.

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